[PDF] A phase I/II study of the oncolytic peptide LTX-315 combined with checkpoint inhibition generates de novo T-cell responses and clinical benefit in patients with …

[PDF] A phase I/II study of the oncolytic peptide LTX-315 combined with checkpoint inhibition generates de novo T-cell responses and clinical benefit in patients with …

J SPICER, A Marabelle, JF Baurain, A Awada… - …, 2018 - lytixbiopharma.com

Page 1. Background LTX-315 is a first in class oncolytic peptide with unique properties to make
cold tumors hot (1,2) Pre-clinical studies of LTX-315 demonstrate: • Unique immunogenic cell
death mode of action by targeting the mitochondria. (3,4) … monotherapy or in combination with …

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