The glucagon-like peptide-1 analogue liraglutide promotes autophagy through the modulation of 5′-AMP-activated protein kinase in INS-1 β-cells under high …

The glucagon-like peptide-1 analogue liraglutide promotes autophagy through the modulation of 5′-AMP-activated protein kinase in INS-1 β-cells under high …

X Miao, Z Gu, Y Liu, M Jin, Y Lu, Y Gong, L Li, C Li - Peptides, 2018 - Elsevier

Abstract Glucagon-like peptide-1 (GLP-1) is a potent therapeutic agent for the treatment of
diabetes and has been proven to protect pancreatic β-cells from glucotoxicity; however, its
mechanisms of action are not entirely understood. Autophagy is a dynamic lysosomal …

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