TNFRSF14 Antibody

Product	TNFRSF14 Antibody
Cat#	100-9-01A
Unit/Weight	100 μg
Unit Price	$311.00
Species Reactivity	H
Tested Application(s)	E, WB, ICC
Brief Description	TNFRSF14 (CT) antibody protect to Herpesvirus entry mediator and upon binding to the herpes simplex virus (HSV) envelope glycoprotein D
Specific Description	Tumor necrosis factor receptor (TNFR) superfamily members are defined by cysteine-rich domains in their extracellular regions that bind TNF-related ligands that share a common structural homology in their extracellular domain. TNFRSF14 was initially identified as the Herpesvirus entry mediator and upon binding to the herpes simplex virus (HSV) envelope glycoprotein D or either of its natural ligands LIGHT and lymphotoxin alpha (LT), activates the transcription factors NF-kappaB and AP-1. Activation of this signal transduction pathway in T cells stimulates T cell proliferation and cytokine production, leading to inflammation and enhanced CTL-mediated tumor immunity, suggesting that these proteins may be useful as potential targets for controlling cellular immune responses.
Storage	TNFRSF14 antibody can be stored at 4°C, stable for one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.