2018年1月6日星期六

[HTML] Crystal structure of the hepatitis C virus NS3 protease domain complexed with a synthetic NS4A cofactor peptide

[HTML] Crystal structure of the hepatitis C virus NS3 protease domain complexed with a synthetic NS4A cofactor peptide

JL Kim, KA Morgenstern, C Lin, T Fox, MD Dwyer… - Cell, 1996 - Elsevier
An estimated 1% of the global human population is infected by hepatitis C viruses (HCVs),
and there are no broadly effective treatments for the debilitating progression of chronic
hepatitis C. A serine protease located within the HCV NS3 protein processes the viral



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