[HTML] Functional gamma‐secretase inhibitors reduce beta‐amyloid peptide levels in brain
HF Dovey, V John, JP Anderson… - Journal of …, 2001 - Wiley Online Library
Abstract Converging lines of evidence implicate the beta-amyloid peptide (Aβ) as causative
in Alzheimer's disease. We describe a novel class of compounds that reduce Aβ production
by functionally inhibiting γ-secretase, the activity responsible for the carboxy-terminal
in Alzheimer's disease. We describe a novel class of compounds that reduce Aβ production
by functionally inhibiting γ-secretase, the activity responsible for the carboxy-terminal
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