2018年1月26日星期五

Secreted forms of β-amyloid precursor protein protect hippocampal neurons against amyloid β-peptide-induced oxidative injury

Secreted forms of β-amyloid precursor protein protect hippocampal neurons against amyloid β-peptide-induced oxidative injury

Y Goodman, MP Mattson - Experimental neurology, 1994 - Elsevier
Abstract Alternative processing of the β-amyloid precursor protein (βAPP) can result in
liberation of either secreted forms of βAPP (App ss), which may play roles in neuronal
plasticity and survival, or amyloid β-peptide (Aβ), which can be neurotoxic. In rat


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