2018年1月5日星期五

Valacyclovir: a substrate for the intestinal and renal peptide transporters PEPT1 and PEPT2

Valacyclovir: a substrate for the intestinal and renal peptide transporters PEPT1 and PEPT2

ME Ganapathy, W Huang, H Wang… - Biochemical and …, 1998 - Elsevier
Valacyclovir is a prodrug of the antiviral agent acyclovir and it does not contain a peptide 
bond in its structure. We studied the interaction of valacyclovir with the peptide transporters
in the human intestinal cell line Caco-2 and the rat kidney proximal tubular cell line SKPT



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