A thiol–ene coupling approach to native peptide stapling and macrocyclization
Y Wang, DHC Chou - Angewandte Chemie International …, 2015 - Wiley Online Library
We report the discovery of a peptide stapling and macrocyclization method using thiol–ene
reactions between two cysteine residues and an α, ω-diene in high yields. This new
approach enabled us to selectively modify cysteine residues in native, unprotected peptides …
reactions between two cysteine residues and an α, ω-diene in high yields. This new
approach enabled us to selectively modify cysteine residues in native, unprotected peptides …
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