2018年6月30日星期六

Beyond cyclosporine A: conformation-dependent passive membrane permeabilities of cyclic peptide natural products

Beyond cyclosporine A: conformation-dependent passive membrane permeabilities of cyclic peptide natural products

CL Ahlbach, KW Lexa, AT Bockus, V Chen… - Future medicinal …, 2015 - Future Science
Many cyclic peptide natural products are larger and structurally more complex than
conventional small molecule drugs. Although some molecules in this class are known to
possess favorable pharmacokinetic properties, there have been few reports on the …


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