In situ conjugation of dithiophenol maleimide polymers and oxytocin for stable and reversible polymer–peptide conjugates

In situ conjugation of dithiophenol maleimide polymers and oxytocin for stable and reversible polymer–peptide conjugates

J Collins, J Tanaka, P Wilson, K Kempe… - Bioconjugate …, 2015 - ACS Publications

The in situ one-pot synthesis of peptide–polymer bioconjugates is reported. Conjugation
occurs efficiently without the need for purification of dithiophenol maleimide functionalized
polymer as a disulfide bridging agent for the therapeutic oxytocin. Conjugation of polymers …

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