2018年6月29日星期五

A redox-responsive drug delivery system based on RGD containing peptide-capped mesoporous silica nanoparticles

A redox-responsive drug delivery system based on RGD containing peptide-capped mesoporous silica nanoparticles

ZY Li, JJ Hu, Q Xu, S Chen, HZ Jia, YX Sun… - Journal of Materials …, 2015 - pubs.rsc.org
In this paper, an intracellular glutathione (GSH) responsive mesoporous silica nanoparticle
(MSN-SS-RGD) was developed as a drug nanocarrier by immobilizing the gatekeeper (RGD
containing peptide) onto MSNs using disulfide bonds. The antitumor drug, DOX was loaded …


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