[HTML] PE and PS lipids synergistically enhance membrane poration by a peptide with anticancer properties

[HTML] PE and PS lipids synergistically enhance membrane poration by a peptide with anticancer properties

NB Leite, A Aufderhorst-Roberts, MS Palma… - Biophysical journal, 2015 - Elsevier

Abstract Polybia-MP1 (MP1) is a bioactive host-defense peptide with known anticancer
properties. Its activity is attributed to excess serine (phosphatidylserine (PS)) on the outer
leaflet of cancer cells. Recently, higher quantities of phosphatidylethanolamine (PE) were …

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