2018年6月29日星期五

[HTML] Current and future implications of basic and translational research on amyloid-β peptide production and removal pathways

[HTML] Current and future implications of basic and translational research on amyloid-β peptide production and removal pathways

C Bohm, F Chen, J Sevalle, S Qamar, R Dodd… - Molecular and Cellular …, 2015 - Elsevier
Inherited variants in multiple different genes are associated with increased risk for
Alzheimer's disease (AD). In many of these genes, the inherited variants alter some aspect
of the production or clearance of the neurotoxic amyloid β-peptide (Aβ). Thus missense …


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