3D HPLC-MS with reversed-phase separation functionality in all three dimensions for large-scale bottom-up proteomics and peptide retention data collection

3D HPLC-MS with reversed-phase separation functionality in all three dimensions for large-scale bottom-up proteomics and peptide retention data collection

V Spicer, P Ezzati, H Neustaeter, RC Beavis… - Analytical …, 2016 - ACS Publications

The growing complexity of proteomics samples and the desire for deeper analysis drive the
development of both better MS instrument and advanced multidimensional separation
schemes. We applied 1D, 2D, and 3D LC-MS/MS separation protocols (all of reversed …

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