2018年8月1日星期三

A spiropyran-based fluorescent probe for the specific detection of β-amyloid peptide oligomers in Alzheimer's disease

A spiropyran-based fluorescent probe for the specific detection of β-amyloid peptide oligomers in Alzheimer's disease

G Lv, A Sun, P Wei, N Zhang, H Lan, T Yi - Chemical Communications, 2016 - pubs.rsc.org
We report a new spiropyran-based fluorescent probe that exhibits high affinity and specificity
towards Aβ oligomers both in vitro and in vivo. This probe can penetrate the blood brain
barrier and specifically target Aβ oligomers in the brains of transgenic mice in models for …


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