A synthetic cell-penetrating dominant-negative ATF5 peptide exerts anticancer activity against a broad spectrum of treatment-resistant cancers

A synthetic cell-penetrating dominant-negative ATF5 peptide exerts anticancer activity against a broad spectrum of treatment-resistant cancers

G Karpel-Massler, BA Horst, C Shu, L Chau… - Clinical Cancer …, 2016 - AACR

Purpose: Despite significant progress in cancer research, many tumor entities still have an
unfavorable prognosis. Activating transcription factor 5 (ATF5) is upregulated in various
malignancies and promotes apoptotic resistance. We evaluated the efficacy and …

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