Attenuation of mechanical pain hypersensitivity by treatment with Peptide5, a connexin-43 mimetic peptide, involves inhibition of NLRP3 inflammasome in nerve …

Attenuation of mechanical pain hypersensitivity by treatment with Peptide5, a connexin-43 mimetic peptide, involves inhibition of NLRP3 inflammasome in nerve …

RS Tonkin, C Bowles, CJ Perera, BA Keating… - Experimental …, 2018 - Elsevier

Abstract Connexin43 (Cx43) hemichannels in spinal cord astrocytes are implicated in the
maintenance of neuropathic pain following peripheral nerve injury. Peptide5 is a Cx43
mimetic peptide that blocks hemichannels. In this study, we investigated the effects of spinal …

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