[HTML] Interplay of histidine residues of the Alzheimer's disease Aβ peptide governs its Zn-induced oligomerization
AN Istrate, SA Kozin, SS Zhokhov, AB Mantsyzov… - Scientific reports, 2016 - nature.com
Conformational changes of Aβ peptide result in its transformation from native monomeric
state to the toxic soluble dimers, oligomers and insoluble aggregates that are hallmarks of
Alzheimer's disease (AD). Interactions of zinc ions with Aβ are mediated by the N-terminal …
state to the toxic soluble dimers, oligomers and insoluble aggregates that are hallmarks of
Alzheimer's disease (AD). Interactions of zinc ions with Aβ are mediated by the N-terminal …
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