2018年8月5日星期日

In vivo Functional Evaluation of Increased Brain Delivery of the Opioid Peptide DAMGO by Glutathione-PEGylated Liposomes

In vivo Functional Evaluation of Increased Brain Delivery of the Opioid Peptide DAMGO by Glutathione-PEGylated Liposomes

A Lindqvist, J Rip, J van Kregten, PJ Gaillard… - Pharmaceutical …, 2016 - Springer
Purpose The purpose of this study was to evaluate formulation factors causing improvement
in brain delivery of a small peptide after encapsulation into a targeted nanocarrier in vivo.
Methods The evaluation was performed in rats using microdialysis, which enabled …


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