[HTML] Relationships between membrane binding, affinity and cell internalization efficacy of a cell-penetrating peptide: penetratin as a case study

[HTML] Relationships between membrane binding, affinity and cell internalization efficacy of a cell-penetrating peptide: penetratin as a case study

ID Alves, C Bechara, A Walrant, Y Zaltsman, CY Jiao… - PLoS …, 2011 - journals.plos.org

Background Penetratin is a positively charged cell-penetrating peptide (CPP) that has the
ability to bind negatively charged membrane components, such as glycosaminoglycans and
anionic lipids. Whether this primary interaction of penetratin with these cell surface …

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