2019年1月27日星期日

The carboxypeptidase ACE shapes the MHC class I peptide repertoire

The carboxypeptidase ACE shapes the MHC class I peptide repertoire

XZ Shen, S Billet, C Lin, D Okwan-Duodu, X Chen… - Nature …, 2011 - nature.com
The surface presentation of peptides by major histocompatibility complex (MHC) class I
molecules is critical to CD8+ T cell–mediated adaptive immune responses.
Aminopeptidases have been linked to the editing of peptides for MHC class I loading, but …


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