2019年4月8日星期一

Late‐Stage Peptide Diversification through Cobalt‐Catalyzed C− H Activation: Sequential Multicatalysis for Stapled Peptides

Late‐Stage Peptide Diversification through Cobalt‐Catalyzed C− H Activation: Sequential Multicatalysis for Stapled Peptides

MM Lorion, N Kaplaneris, J Son… - Angewandte Chemie …, 2019 - Wiley Online Library
Bioorthogonal late‐stage diversification of structurally complex peptides has enormous
potential for drug discovery and molecular imaging. In recent years, transition‐metal‐
catalyzed C− H activation has emerged as an increasingly viable tool for peptide  …


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