2019年4月8日星期一

Mechanistic Probes for the Epimerization Domain of Nonribosomal Peptide Synthetases

Mechanistic Probes for the Epimerization Domain of Nonribosomal Peptide Synthetases

WE Kim, A Patel, GH Hur, P Tufar, MG Wuo… - …, 2019 - Wiley Online Library
Nonribosomal peptide synthetases (NRPSs) are responsible for the synthesis of a variety of
bioactive natural products with clinical and economic significance. Interestingly, these large
multimodular enzyme machineries incorporate nonproteinogenic d‐amino acids through the …


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