2018年5月31日星期四

A Novel Membrane Peptide that Inhibits Cell Migration by Activation of the Receptor Tyrosine Kinase EphA2

A Novel Membrane Peptide that Inhibits Cell Migration by Activation of the Receptor Tyrosine Kinase EphA2

JM Westerfield, DS Alves, X Shi, VP Nguyen… - Biophysical …, 2018 - cell.com
Misregulation of the signaling axis formed by EphA2 and its ligand, ephrinA1, causes
aberrant cell-cell contacts and leads to cellular transformation and malignancy in cancer.
However, the activation mechanism of EphA2 is poorly understood. Also, solid tumors …


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