2018年5月27日星期日

[HTML] WT1 peptide vaccine in Montanide in contrast to poly ICLC, is able to induce WT1-specific immune response with TCR clonal enrichment in myeloid leukemia

[HTML] WT1 peptide vaccine in Montanide in contrast to poly ICLC, is able to induce WT1-specific immune response with TCR clonal enrichment in myeloid leukemia

H Liu, Y Zha, N Choudhury… - Experimental …, 2018 - ehoonline.biomedcentral.com
The optimal strategy for vaccination to induce CD8+ T cell responses against WT1 is not
known. A pilot randomized study in HLA-A02+ patients to receive vaccination with WT1 in
Montanide or in poly ICLC, a TLR3 agonist, to explore the novel immune adjuvant was …


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