2018年5月28日星期一

An intramolecular tryptophan-condensation approach for peptide stapling

An intramolecular tryptophan-condensation approach for peptide stapling

EYL Hui, B Rout, YS Tan, CS Verma… - Organic & …, 2018 - pubs.rsc.org
Stapled peptides are gaining tremendous interest as next-generation therapeutic agents to
target protein–protein interactions. Herein, we report an intramolecular peptide stapling
method which links two tryptophan residues at the C2 position of the indole moieties via acid …


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