[HTML] Membrane permeabilizing amphiphilic peptide delivers recombinant transcription factor and CRISPR-Cas9/Cpf1 ribonucleoproteins in hard-to-modify cells

[HTML] Membrane permeabilizing amphiphilic peptide delivers recombinant transcription factor and CRISPR-Cas9/Cpf1 ribonucleoproteins in hard-to-modify cells

T Del'Guidice, JP Lepetit-Stoffaes, LJ Bordeleau… - PloS one, 2018 - journals.plos.org

Delivery of recombinant proteins to therapeutic cells is limited by a lack of efficient methods.
This hinders the use of transcription factors or Clustered Regularly Interspaced Short
Palindromic Repeats (CRISPR) ribonucleoproteins to develop cell therapies. Here, we …

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