… of Tubulin Acetylation from Pepsin-Digested Rat Brain Tissue Using a Novel Stable Isotope Standard and Capture by Anti-Peptide Antibody (SISCAPA) Method

… of Tubulin Acetylation from Pepsin-Digested Rat Brain Tissue Using a Novel Stable Isotope Standard and Capture by Anti-Peptide Antibody (SISCAPA) Method

X Yang, SX Naughton, Z Han, M He, YG Zheng… - Analytical …, 2018 - ACS Publications

Acetylation of α-tubulin at Lys-40 is a potential biomarker for cognitive deficits in various
neurological disorders. However, this key PTM has not been previously studied with mass
spectrometry, due to the inadequate distribution of tryptic cleavage sites. Following peptic …

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