Attacking Ras-driven cancers: Engineering a peptide inhibitor for Cdc42
GJN Tetley - 2018 - repository.cam.ac.uk
Prior work has indicated that preventing Cdc42 interacting with its downstream effector
proteins can reverse Ras-driven oncogenesis. The experiments demonstrating this used the
G protein binding region (GBD) of the Cdc42-specific effector ACK, which is 42 amino acids …
proteins can reverse Ras-driven oncogenesis. The experiments demonstrating this used the
G protein binding region (GBD) of the Cdc42-specific effector ACK, which is 42 amino acids …
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