2018年5月26日星期六

An intramolecular tryptophan-condensation approach for peptide stapling

An intramolecular tryptophan-condensation approach for peptide stapling

EYL Hui, B Rout, YS Tan, CS Verma… - Organic & …, 2018 - pubs.rsc.org
Stapled peptides are gaining tremendous interest as next-generation therapeutic agents to
target protein–protein interactions. Herein, we report an intramolecular peptide stapling
method which links two tryptophan residues at the C2 position of the indole moieties via acid …


For custom peptides, please visit www.pepmic.com. Our peptide services including but not limited to:
*Peptide Synthesis: From short peptides to long peptides, linear peptides to cyclic peptides.
*Peptide Modifications: Peptide-protein conjugation, D-amino acid peptides, isotope peptides, fluorescent peptides, multiple antigen peptides, multiple disulfide bridge peptides, phosphopeptides etc.
*Catalog Peptides: ACE Inhibitors, Amyloids & Related Peptides, Antimicrobial Peptides, Apelin Peptides, Myelin Oligodendrocyte Glycoprotein (MOG) Peptides, TAT Proteins etc.
*Peptide Salt: TFA, Desalt, Acetate, HCl.
*Peptide Purity: From crude to >99.5%.
*Production Capacity: From mg to kg, with a capacity of synthesizing 15,000 peptides/month.
*Peptide Library Synthesis: Alanine Scan, Overlapping, Positional Scan, T-cell Truncated, Scrambled ect.

Eva He
eva@pepmic.com
Pepmic Co., Ltd
www.pepmic.com


没有评论:

发表评论