Total Synthesis of the Highly N-Methylated Acetylene-Containing Anticancer Peptide Jahanyne
A Siow, G Opiyo, I Kavianinia, FF Li, DP Furkert… - Organic …, 2018 - ACS Publications
The first total synthesis of the highly N-methylated acetylene-containing lipopeptide
jahanyne, an apoptosis-inducing natural product from marine cyanobacteria, is reported. A
late-stage solution-phase coupling enabled introduction of the C-terminal ketone pyrrolidine …
jahanyne, an apoptosis-inducing natural product from marine cyanobacteria, is reported. A
late-stage solution-phase coupling enabled introduction of the C-terminal ketone pyrrolidine …
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