2018年5月29日星期二

Identification of Lasso Peptide Topologies Using Native nESI-Trapped Ion Mobility Spectrometry-Mass Spectrometry.

Identification of Lasso Peptide Topologies Using Native nESI-Trapped Ion Mobility Spectrometry-Mass Spectrometry.

KDF Jeanne, J Moreno, JD Hegemann, S Zirah… - Analytical …, 2018 - europepmc.org
Lasso peptides are ribosomally synthesized and post-translationally modified peptides
(RiPPs) characterized by a mechanically interlocked topology. In contrast to their branched-
cyclic forms, lasso peptides have higher stability and have become a scaffold for drug …


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