Development of Pseudomonas aeruginosa Lectin LecA Inhibitor by using Bivalent Galactosides Supported on Polyproline Peptide Scaffolds
SF Huang, CH Lin, YT Lai, CL Tsai… - Chemistry–An Asian …, 2018 - Wiley Online Library
LecA is a galactose‐binding tetrameric lectin from Pseudomonas aeruginosa involved in
infection and biofilm formation. The emergent antibiotic resistance of P. aeruginosa has
made LecA a promising pharmaceutical target to treat such infections. To develop LecA …
infection and biofilm formation. The emergent antibiotic resistance of P. aeruginosa has
made LecA a promising pharmaceutical target to treat such infections. To develop LecA …
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