ApoA-I Mimetic Peptide 4F Reduces Age-Related Lipid Deposition in Murine Bruch's Membrane and Causes Its Structural Remodeling

ApoA-I Mimetic Peptide 4F Reduces Age-Related Lipid Deposition in Murine Bruch's Membrane and Causes Its Structural Remodeling

M Rudolf, A Mir Mohi Sefat, Y Miura, A Tura… - Current eye …, 2018 - Taylor & Francis

Purpose: Accumulation of lipoprotein-derived lipids including esterified and unesterified
cholesterol in Bruch's membrane of human eyes is a major age-related change involved in
initiating and sustaining soft drusen in age-related macular degeneration (AMD). The …

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