[HTML] Whole genome duplications have provided teleosts with many roads to peptide loaded MHC class I molecules

[HTML] Whole genome duplications have provided teleosts with many roads to peptide loaded MHC class I molecules

U Grimholt - BMC evolutionary biology, 2018 - bmcevolbiol.biomedcentral.com

In sharks, chickens, rats, frogs, medaka and zebrafish there is haplotypic variation in MHC
class I and closely linked genes involved in antigen processing, peptide translocation and
peptide loading. At least in chicken, such MHCIa haplotypes of MHCIa, TAP2 and Tapasin …

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