2018年8月1日星期三

[HTML] Phosphorylation of the amyloid β-peptide at Ser26 stabilizes oligomeric assembly and increases neurotoxicity

[HTML] Phosphorylation of the amyloid β-peptide at Ser26 stabilizes oligomeric assembly and increases neurotoxicity

S Kumar, O Wirths, K Stüber, P Wunderlich, P Koch… - Acta …, 2016 - Springer
Aggregation and toxicity of the amyloid β-peptide (Aβ) are considered as critical events in
the initiation and progression of Alzheimer's disease (AD). Recent evidence indicated that
soluble oligomeric Aβ assemblies exert pronounced toxicity, rather than larger fibrillar …

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