2018年8月2日星期四

Structural determinants of binding the seven-transmembrane domain of the glucagon-like peptide-1 receptor

Structural determinants of binding the seven-transmembrane domain of the glucagon-like peptide-1 receptor

D Yang, C de Graaf, L Yang, G Song, A Dai… - Journal of Biological …, 2016 - ASBMB
The glucagon-like peptide-1 receptor (GLP-1R) belongs to the secretin-like (class B) family
of G protein-coupled receptors (GPCRs). Members of the class B family are distinguished by
their large extracellular domain (ECD), which works cooperatively with the canonical seven …


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