Inhibition of pre‐existing natural periodontitis in non‐human primates by a locally administered peptide inhibitor of complement C3

Inhibition of pre‐existing natural periodontitis in non‐human primates by a locally administered peptide inhibitor of complement C3

T Maekawa, RA Briones, RRG Resuello… - Journal of clinical …, 2016 - Wiley Online Library

Aim Human periodontitis is associated with overactivation of complement, which is triggered
by different mechanisms converging on C3, the central hub of the system. We assessed
whether the C3 inhibitor Cp40 inhibits naturally occurring periodontitis in non‐human …

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