Nonclinical pharmacokinetics disposition, and drug-drug interaction potential of a novel D-amino acid peptide agonist of the calcium sensing receptor AMG 416 …
R Subramanian, X Zhu, S Kerr, M Fitzsimmons… - Drug Metabolism and …, 2016 - ASPET
AMG 416 (Etelcalcetide) is a novel synthetic peptide agonist of the calcium-sensing receptor
composed of a linear chain of seven D-amino acids (referred to as the" D-amino acid
backbone") with a D-cysteine linked to an L-cysteine via a disulfide bond. AMG 416 contains …
composed of a linear chain of seven D-amino acids (referred to as the" D-amino acid
backbone") with a D-cysteine linked to an L-cysteine via a disulfide bond. AMG 416 contains …
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