2018年10月22日星期一

Discovery of peptide ligands through docking and virtual screening at nicotinic acetylcholine receptor homology models

Discovery of peptide ligands through docking and virtual screening at nicotinic acetylcholine receptor homology models

AE Leffler, A Kuryatov, HA Zebroski… - Proceedings of the …, 2017 - National Acad Sciences
Venom peptide toxins such as conotoxins play a critical role in the characterization of
nicotinic acetylcholine receptor (nAChR) structure and function and have potential as
nervous system therapeutics as well. However, the lack of solved structures of conotoxins …


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