The hypothalamic glucagon-like peptide 1 receptor is sufficient but not necessary for the regulation of energy balance and glucose homeostasis in mice

The hypothalamic glucagon-like peptide 1 receptor is sufficient but not necessary for the regulation of energy balance and glucose homeostasis in mice

MA Burmeister, JE Ayala, H Smouse… - Diabetes, 2017 - Am Diabetes Assoc

Pharmacological activation of the hypothalamic glucagon-like peptide 1 (GLP-1) receptor
(GLP-1R) promotes weight loss and improves glucose tolerance. This demonstrates that the
hypothalamic GLP-1R is sufficient but does not show whether it is necessary for the effects of …

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