A D‐Peptide Ligand of Nicotine Acetylcholine Receptors for Brain‐Targeted Drug Delivery

A D‐Peptide Ligand of Nicotine Acetylcholine Receptors for Brain‐Targeted Drug Delivery

X Wei, C Zhan, Q Shen, W Fu, C Xie, J Gao… - Angewandte …, 2015 - Wiley Online Library

Lysosomes of brain capillary endothelial cells are implicated in nicotine acetylcholine
receptor (nAChR)‐mediated transcytosis and act as an enzymatic barrier for the transport of
peptide ligands to the brain. A d‐peptide ligand of nAChRs (termed DCDX), which binds to …

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