The G protein-coupled receptor family C group 6 subtype A (GPRC6A) receptor is involved in amino acid-induced glucagon-like peptide-1 secretion from GLUTag …

The G protein-coupled receptor family C group 6 subtype A (GPRC6A) receptor is involved in amino acid-induced glucagon-like peptide-1 secretion from GLUTag …

M Oya, T Kitaguchi, R Pais, F Reimann… - Journal of Biological …, 2013 - ASBMB

Background: The molecular mechanisms underlying GLP-1 secretion induced by amino
acids from intestinal L cells are not fully understood. Results: The l-amino acid-sensing
GPRC6A receptor is expressed in the clonal L cell GLUTag. Activation of GPRC6A by l …

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