2018年12月27日星期四

High-affinity cyclic peptide matriptase inhibitors

High-affinity cyclic peptide matriptase inhibitors

P Quimbar, U Malik, CP Sommerhoff, Q Kaas… - Journal of Biological …, 2013 - ASBMB
Results: Elucidation of structure-activity relationships for SFTI-1 and MCoTI-II was used to
design inhibitors with enhanced inhibitory activity. Conclusion: An analogue of MCoTI-II is
one of the most potent inhibitors of matriptase. Significance: These results provide a solid …


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