Development and characterization of self-assembling nanoparticles using a bio-inspired amphipathic peptide for gene delivery

Development and characterization of self-assembling nanoparticles using a bio-inspired amphipathic peptide for gene delivery

HO McCarthy, J McCaffrey, CM McCrudden… - Journal of Controlled …, 2014 - Elsevier

The design of a non-viral gene delivery vehicle capable of delivering and releasing a
functional nucleic acid cargo intracellularly remains a formidable challenge. For systemic
gene therapy to be successful a delivery vehicle is required that protects the nucleic acid …

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