[HTML] Mitochondrial import and degradation of amyloid-β peptide

[HTML] Mitochondrial import and degradation of amyloid-β peptide

CM Pinho, PF Teixeira, E Glaser - Biochimica et Biophysica Acta (BBA) …, 2014 - Elsevier

Mitochondrial dysfunctions associated with amyloid-β peptide (Aβ) accumulation in
mitochondria have been observed in Alzheimer's disease (AD) patients' brains and in AD
mice models. Aβ is produced by sequential action of β-and γ-secretases cleaving the …

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