Amyloid-β peptide protects against microbial infection in mouse and worm models of Alzheimer's disease
DKV Kumar, SH Choi, KJ Washicosky… - Science translational …, 2016 - stm.sciencemag.org
The amyloid-β peptide (Aβ) is a key protein in Alzheimer's disease (AD) pathology. We
previously reported in vitro evidence suggesting that Aβ is an antimicrobial peptide. We
present in vivo data showing that Aβ expression protects against fungal and bacterial …
previously reported in vitro evidence suggesting that Aβ is an antimicrobial peptide. We
present in vivo data showing that Aβ expression protects against fungal and bacterial …
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