2019年1月6日星期日

Alternative peptide repertoire of HLA-E reveals a binding motif that is strikingly similar to HLA-A2

Alternative peptide repertoire of HLA-E reveals a binding motif that is strikingly similar to HLA-A2

MH Lampen, C Hassan, M Sluijter, A Geluk… - Molecular …, 2013 - Elsevier
The non-classical HLA-E is a conserved class I molecule that mainly presents monomorphic
leader peptides derived from other HLA class I molecules. These leader peptides comprise
an optimized sequence for tight and deep binding into the HLA-E groove. In a TAP-deficient …


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