2019年1月24日星期四

CD52 (HI186) Antibody

Product  CD52 (HI186) Antibody
Cat#  100-26-28A
Unit/Weight  2 ml
Unit Price  $299.00
Species Reactivity  H
Tested Application(s)  FC
Brief Description  Mouse Monoclonal Antibody, FITC-conjugated Antibody
Specific Description  The CD52 (HI186) antibody recognizes a 25-29 kDa glycosylphosphatidylinositol (GPI)-anchored single chain glycoprotein typically expressed at high levels on thymocytes, lymphocytes, NK cells, monocytes/macrophages. CD52 is expressed at 2% on some granulocytes and epithelial cells of male reproductive tract, and also expressed at variable levels on the majority of lymphoid malignancies, but not on erythrocytes and platelets. A somatic defect in the synthesis of GPI anchors causes a lack of CD52 antigen on cell surface on lymphocytes from patients with paroxysmal nocturnal haemoglobinuria (PNH) . CD52 may be used to diagnose PNH besides CD55 and CD59. All CD52 antibodies are characterized by a strong lytic activity with human complement, irrespective of antibody isotype.
Storage  Store at 4°C. Product is guaranteed 6 months from the date of shipment.

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