Product | CD52 (HI186) Antibody |
Cat# | 100-26-28A |
Unit/Weight | 2 ml |
Unit Price | $299.00 |
Species Reactivity | H |
Tested Application(s) | FC |
Brief Description | Mouse Monoclonal Antibody, FITC-conjugated Antibody |
Specific Description | The CD52 (HI186) antibody recognizes a 25-29 kDa glycosylphosphatidylinositol (GPI)-anchored single chain glycoprotein typically expressed at high levels on thymocytes, lymphocytes, NK cells, monocytes/macrophages. CD52 is expressed at 2% on some granulocytes and epithelial cells of male reproductive tract, and also expressed at variable levels on the majority of lymphoid malignancies, but not on erythrocytes and platelets. A somatic defect in the synthesis of GPI anchors causes a lack of CD52 antigen on cell surface on lymphocytes from patients with paroxysmal nocturnal haemoglobinuria (PNH) . CD52 may be used to diagnose PNH besides CD55 and CD59. All CD52 antibodies are characterized by a strong lytic activity with human complement, irrespective of antibody isotype. |
Storage | Store at 4°C. Product is guaranteed 6 months from the date of shipment. |
Peptide synthesis/Peptide Library Synthesis/Peptide Modification/Antibody Preparation Eve He eve@pepmic.com www.pepmic.com
2019年1月24日星期四
CD52 (HI186) Antibody
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