2019年1月2日星期三

[HTML] Inactivation of the cardiomyocyte glucagon-like peptide-1 receptor (GLP-1R) unmasks cardiomyocyte-independent GLP-1R-mediated cardioprotection

[HTML] Inactivation of the cardiomyocyte glucagon-like peptide-1 receptor (GLP-1R) unmasks cardiomyocyte-independent GLP-1R-mediated cardioprotection

JR Ussher, LL Baggio, JE Campbell, EE Mulvihill… - Molecular …, 2014 - Elsevier
GLP-1R agonists improve outcomes in ischemic heart disease. Here we studied GLP-1R-
dependent adaptive and cardioprotective responses to ventricular injury. Glp1r−/− hearts
exhibited chamber-specific differences in gene expression, but normal mortality and left …


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